Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 5/20 | 0.51 |
| ▸ | CACNA1I | Q9P0X4 | 4/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | RIOK2 | Q9BVS4 | 7/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 3/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.42 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987654 | 0.88 | RIOK2 (0.51) | CACNA1HCACNA1ICACNA1GCNR2KCNH2 | |
| SCHEMBL8987716 | 0.85 | MAPK10 (0.50) | CACNA1HCACNA1ICACNA1GCNR2KCNH2 | |
| SCHEMBL8987841 | 0.84 | MAPK14 (0.50) | CACNA1HRIOK2MAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8987643 | 0.83 | MAPK10 (0.46) | CACNA1HCACNA1ICACNA1GCNR2KCNH2 | |
| SCHEMBL8988094 | 0.83 | MAPK10 (0.46) | CACNA1HCACNA1ICACNA1GCNR2KCNH2 | |
| SCHEMBL8987961 | 0.83 | MAPK10 (0.45) | CACNA1HCACNA1ICACNA1GCNR2KCNH2 | |
| SCHEMBL8988044 | 0.82 | MAPK10 (0.44) | CACNA1HCACNA1ICACNA1GCNR2KCNH2 | |
| SCHEMBL8987985 | 0.82 | MAPK10 (0.47) | CACNA1HCACNA1ICACNA1GCNR2KCNH2 | |
| SCHEMBL8987786 | 0.80 | CACNA1I (0.50) | CACNA1HCACNA1ICACNA1GCNR2KCNH2 | |
| SCHEMBL8987736 | 0.80 | SMN1; SMN2 (0.44) | CACNA1HCACNA1ICACNA1GCNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |