Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.34 |
| ▸ | RBP4 | P02753 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987503 | 0.88 | POLB (0.40) | POLBGAAHCRTR1HCRTR2MEN1 | |
| SCHEMBL8987671 | 0.84 | POLB (0.37) | POLBGAAHCRTR1HCRTR2RBP4 | |
| SCHEMBL8987561 | 0.77 | HDAC4 (0.36) | HCRTR1HCRTR2MEN1KMT2AMAPT | |
| SCHEMBL9043151 | 0.76 | HTT (0.34) | POLBGAAMEN1HTTKMT2A | |
| SCHEMBL8987728 | 0.76 | POLB (0.38) | POLBGAAHCRTR1HCRTR2MEN1 | |
| SCHEMBL9043112 | 0.73 | ADORA2A (0.37) | POLBMEN1HTTKMT2ARAB9A | |
| SCHEMBL27311061 | 0.73 | POLB (0.35) | POLBHCRTR1HCRTR2RBP4MEN1 | |
| SCHEMBL8987920 | 0.73 | L3MBTL1 (0.34) | POLBHCRTR1HCRTR2MEN1HTT | |
| SCHEMBL8987616 | 0.73 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL9043406 | 0.72 | POLB (0.35) | POLBHCRTR1HCRTR2MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441747-B1 | Microbicide agent | CIBA GEIGY AG (CH) | 1996-07-03 | — | — | EP | disclosed |
| US-5120741-A | Crop protection against phytopathogenic microorganisms | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0441747-A2 | Microbicide agent | CIBA-GEIGY AG (CH) | 1991-08-14 | — | — | EP | disclosed |