Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8988245

CCCCCCCCCCCCC=C(C(=O)O)C(C)(CC)CCCCCCCCCCCC.N

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.51
BLM P54132 3/20 0.40
HSD17B10 Q99714 3/20 0.40
GMNN O75496 2/20 0.40
USP2 O75604 2/20 0.40
CYP1A2 P05177 2/20 0.40
POLB P06746 2/20 0.40
CYP2C9 P11712 2/20 0.40
APEX1 P27695 2/20 0.40
CYP2C19 P33261 2/20 0.40
RECQL P46063 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
TERT O14746 3/20 0.39
MAPT P10636 2/20 0.39
FABP4 P15090 2/20 0.39
PTPN1 P18031 2/20 0.39
PPARG P37231 2/20 0.39
PPARD Q03181 2/20 0.39
PPARA Q07869 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11528107 0.85 EP300 (0.39) EP300HSD17B10FABP4PTPN1PPARG
SCHEMBL11528101 0.85 EP300 (0.39) EP300HSD17B10FABP4PTPN1PPARG
SCHEMBL4358637 0.80 EP300 (0.58) EP300BLMHSD17B10GMNNUSP2
SCHEMBL5271639 0.79 EP300 (0.62) EP300BLMHSD17B10GMNNUSP2
SCHEMBL7124103 0.79 EP300 (0.62) EP300BLMHSD17B10GMNNUSP2
SCHEMBL9064054 0.77 EP300 (0.51) EP300BLMHSD17B10GMNNUSP2
Ammonia Solution, Strong SCHEMBL28708430 0.77 CES2 (0.42) HSD17B10FABP4PTPN1PPARGPPARD
Ammonia Solution, Strong SCHEMBL7188535 0.77 EP300 (0.38) EP300HSD17B10FABP4PTPN1PPARG
SCHEMBL20915417 0.75 CES2 (0.44) HSD17B10FABP4PTPN1PPARGPPARD
SCHEMBL20936468 0.75 CES2 (0.44) HSD17B10FABP4PTPN1PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0442638-B1 Polymeric compounds DU PONT UK (GB) 1996-07-10 EP disclosed
US-5278022-A Photopolymerizable E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-01-11 US disclosed
EP-0358400-B1 Improvements in or relating to polymeric compounds DU PONT (US) 1993-11-10 EP disclosed
US-5162431-A Photosensitive Binders DU PONT-HOWSON LIMITED (GB) 1992-11-10 US disclosed
US-5120799-A POLYMERIC COMPOUNDS HAVING PENDANT SULPHONATO GROUPS AND METHOD OF PRODUCING THE POLYMERIC COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (INC.) (US) 1992-06-09 US disclosed
EP-0442638-A2 Polymeric compounds Du Pont (UK) Limited (GB) 1991-08-21 EP disclosed
EP-0358400-A2 Improvements in or relating to polymeric compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-14 EP disclosed