Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8988618 | 0.99 | HRH3 (0.39) | HRH3HDAC1PTPN1EPHX2TP53 | |
| SCHEMBL8988731 | 0.90 | PPARD (0.39) | HRH3TP53PTGS1PTGS2KDM4E | |
| Hydrochloric Acid SCHEMBL8988795 | 0.89 | PPARD (0.39) | HRH3TP53PTGS1PTGS2KDM4E | |
| SCHEMBL8988689 | 0.88 | ITGB3 (0.43) | HRH3HDAC1PTPN1 | |
| SCHEMBL8988853 | 0.88 | HRH3 (0.37) | HRH3HDAC1PTPN1TP53CTSD | |
| Hydrochloric Acid SCHEMBL8988496 | 0.87 | ITGB3 (0.43) | HRH3HDAC1PTPN1 | |
| Hydrochloric Acid SCHEMBL8988502 | 0.87 | ITGB3 (0.43) | HRH3HDAC1PTPN1 | |
| SCHEMBL8988553 | 0.87 | CYP11B1 (0.43) | HRH3HDAC1PTPN1MAPTKDM4E | |
| SCHEMBL8988630 | 0.86 | PTPN1 (0.40) | HRH3HDAC1PTPN1CTSDPTGS1 | |
| Hydrochloric Acid SCHEMBL8988806 | 0.84 | HRH3 (0.36) | HRH3HDAC1PTPN1EPHX2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489693-A | ANTICOAGULANTS | DR. KARK THOMAE, GMBH (DE) | 1996-02-06 | — | — | US | disclosed |
| EP-0567968-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |