Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894080 | 0.84 | TRPV3 (0.58) | TRPV3 | |
| SCHEMBL893694 | 0.84 | TRPV3 (0.65) | TRPV3 | |
| SCHEMBL12615472 | 0.80 | TRPV3 (0.68) | TRPV3 | |
| SCHEMBL12615426 | 0.79 | TRPV3 (0.67) | TRPV3 | |
| SCHEMBL28267570 | 0.78 | MEN1 (0.54) | TRPV3 | |
| SCHEMBL12615400 | 0.76 | TRPV3 (0.69) | TRPV3 | |
| SCHEMBL18002987 | 0.75 | TRPV3 (0.53) | TRPV3 | |
| SCHEMBL8030882 | 0.75 | TRPV3 (0.51) | TRPV3 | |
| SCHEMBL5250133 | 0.75 | S1PR1 (0.55) | TRPV3 | |
| SCHEMBL2666272 | 0.75 | TRPV3 (0.51) | TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545645-A | Heterocyclic derivatives in the treatment of ischaemia and related diseases | SYNTEX PHARMACEUTICALS, LIMITED (GB) | 1996-08-13 | — | — | US | disclosed |
| US-5428037-A | Piperazine derivatives; calcium and sodium channel antagonists | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1995-06-27 | — | — | US | disclosed |