Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 9/20 | 0.34 |
| ▸ | ANPEP | P15144 | 3/20 | 0.33 |
| ▸ | LAP3 | P28838 | 2/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.31 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2304432 | 0.80 | KDM4C (0.39) | LAP3 | |
| SCHEMBL11535258 | 0.79 | SMPD1 (0.37) | ENPP2LAP3 | |
| SCHEMBL2302042 | 0.79 | KDM4C (0.41) | LAP3 | |
| SCHEMBL7950976 | 0.79 | KDM4C (0.41) | LAP3 | |
| SCHEMBL7947910 | 0.79 | KDM4C (0.41) | LAP3 | |
| SCHEMBL7570633 | 0.79 | KDM4C (0.41) | LAP3 | |
| SCHEMBL4943737 | 0.75 | CA1 (0.37) | ANPEPLAP3ERAP1 | |
| SCHEMBL4054598 | 0.72 | KDM1A (0.37) | — | |
| SCHEMBL8989553 | 0.71 | ENPP2 (0.35) | ENPP2LPAR6LPAR1LPAR4LPAR5 | |
| SCHEMBL11516995 | 0.70 | CA1 (0.44) | ANPEPLAP3ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534547-A | Prostaglandins of the D series, and tranquilizers and soporifics containing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1996-07-09 | — | — | US | disclosed |
| US-5137915-A | PROSTAGLANDINS OF THE D SERIES, AND TRANQUILIZERS AND SOPORIFICS CONTAINING THE SAME | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0281239-B1 | PROSTAGLANDINS OF THE D SERIES, AND TRANQUILIZERS AND SOPORIFICS CONTAINING THE SAME | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-03-25 | — | — | EP | disclosed |
| US-5073569-A | 13,14-dihydro-15-keto- | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0281239-A2 | Prostaglandins of the D series, and tranquilizers and soporifics containing the same | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1988-09-07 | — | — | EP | disclosed |