Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916520 | 1.00 | CYP2D6 (0.30) | CYP2D6CYP2C19HIF1A | |
| SCHEMBL8918330 | 0.73 | — | — | |
| SCHEMBL8918378 | 0.70 | — | — | |
| SCHEMBL11197638 | 0.69 | — | — | |
| SCHEMBL11638215 | 0.68 | — | — | |
| SCHEMBL11037170 | 0.67 | TSHR (0.38) | CYP2C19 | |
| SCHEMBL9738158 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL13444602 | 0.66 | — | — | |
| SCHEMBL11246632 | 0.63 | — | — | |
| SCHEMBL13589959 | 0.63 | CYP2C19 (0.41) | CYP2D6CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563250-A | Cleavable conjugates for the delivery and release of agents in native form | NEORX CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |