Bromide

Bromide

SCHEMBL8990164

CCCCC/C=C\C/C=C\C/C=C\CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.45
FAAH O00519 1/20 0.44
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
HIF1A Q16665 1/20 0.44
PPARG P37231 5/20 0.44
ALDH1A1 P00352 5/20 0.44
PPARD Q03181 4/20 0.44
PPARA Q07869 4/20 0.44
F7 P08709 4/20 0.44
F3 P13726 4/20 0.44
FFAR1 O14842 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP19A1 P11511 2/20 0.44
FABP4 P15090 2/20 0.44
HPGD P15428 2/20 0.44
ALOX15 P16050 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL11067074 0.97 EPHX2 (0.45) EPHX2FAAHCNR1CNR2HIF1A
Iodide SCHEMBL11067078 0.97 EPHX2 (0.45) EPHX2FAAHCNR1CNR2HIF1A
Iodide SCHEMBL19032656 0.93 HIF1A (0.47) EPHX2FAAHCNR1CNR2HIF1A
Iodide SCHEMBL11070153 0.93 HIF1A (0.47) EPHX2FAAHCNR1CNR2HIF1A
Iodide SCHEMBL10731909 0.93 HIF1A (0.47) EPHX2FAAHCNR1CNR2HIF1A
Iodide SCHEMBL11062979 0.92 SOAT2 (0.46) EPHX2FAAHCNR1CNR2HIF1A
Iodide SCHEMBL11062977 0.92 SOAT2 (0.46) EPHX2FAAHCNR1CNR2HIF1A
Bromide SCHEMBL27230650 0.90 HIF1A (0.47) EPHX2FAAHCNR1CNR2HIF1A
Bromide SCHEMBL27211909 0.90 HIF1A (0.47) EPHX2FAAHCNR1CNR2HIF1A
Iodide SCHEMBL8438793 0.87 HIF1A (0.47) EPHX2FAAHCNR1CNR2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024172932-A1 ENDOCANNABINOID LIGANDS AND RELATED ANALOGS NORTHEASTERN UNIVERSITY (US) 2024-08-22 WO disclosed
US-5504107-A ANTICOAGULANTS, PREVENTING ATHEROSCLEROSIS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1996-04-02 US disclosed