Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16845561 | 0.83 | TEAD1 (0.44) | SLC6A2SLC6A4SLC6A3EPHX2TEAD1 | |
| SCHEMBL20858622 | 0.82 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3TP53KMT2A | |
| SCHEMBL24168852 | 0.79 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3TP53KMT2A | |
| SCHEMBL8990348 | 0.78 | CARM1 (0.53) | MGLL | |
| SCHEMBL148028 | 0.78 | HRH1 (0.50) | SLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL22816111 | 0.76 | HTR2C (0.57) | DRD2 | |
| SCHEMBL16571060 | 0.76 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3TP53KMT2A | |
| SCHEMBL3118322 | 0.76 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3TP53KMT2A | |
| SCHEMBL1231217 | 0.76 | SLC6A4 (0.65) | SLC6A2SLC6A4SLC6A3TP53KMT2A | |
| SCHEMBL18186079 | 0.76 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |