Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 9/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524763 | 0.83 | CARM1 (0.50) | CARM1PRMT6IDO1DRD4SIGMAR1 | |
| SCHEMBL30754913 | 0.81 | CARM1 (0.62) | CARM1PRMT6IDO1DRD4SIGMAR1 | |
| SCHEMBL720768 | 0.80 | OPRM1 (0.56) | CARM1PRMT6SIGMAR1TMEM97 | |
| SCHEMBL8990301 | 0.78 | SLC6A2 (0.54) | MGLL | |
| SCHEMBL2297042 | 0.78 | CARM1 (0.58) | CARM1PRMT6IDO1DRD4SIGMAR1 | |
| SCHEMBL102306 | 0.78 | CARM1 (0.58) | CARM1PRMT6IDO1DRD4SIGMAR1 | |
| SCHEMBL8633784 | 0.76 | CARM1 (0.57) | CARM1PRMT6IDO1DRD4SIGMAR1 | |
| SCHEMBL24780705 | 0.74 | CARM1 (0.55) | CARM1PRMT6IDO1DRD4SIGMAR1 | |
| SCHEMBL10686275 | 0.74 | OPRM1 (0.54) | CARM1PRMT6SIGMAR1TMEM97 | |
| SCHEMBL24168671 | 0.74 | SLC6A4 (0.59) | CARM1PRMT6IDO1DRD4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |