SCHEMBL8990538

SCHEMBL8990538

CC1CCC(C)(OC(=O)O)CC1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.34
CYP2C9 P11712 1/20 0.34
CYP1A2 P05177 1/20 0.32
FFAR3 O14843 1/20 0.32
SCN1A P35498 2/20 0.32
SCN2A Q99250 2/20 0.32
SCN3A Q9NY46 2/20 0.32
MAPK1 P28482 2/20 0.30
TP53 P04637 1/20 0.30
NFKB1 P19838 1/20 0.30
THPO P40225 1/20 0.30
STAT6 P42226 1/20 0.30
HIF1A Q16665 1/20 0.30
NPC1 O15118 1/20 0.30
GMNN O75496 1/20 0.30
LMNA P02545 1/20 0.30
MTOR P42345 1/20 0.30
RAB9A P51151 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3670104 0.81
SCHEMBL11567957 0.81 SLC1A2 (0.32) FFAR3SCN1ASCN2ASCN3A
SCHEMBL11085265 0.81 SLC1A2 (0.32) FFAR3SCN1ASCN2ASCN3A
SCHEMBL3267324 0.79 SCN1A (0.30) CYP2C19FFAR3SCN1ASCN2ASCN3A
Hydrochloric Acid SCHEMBL4398568 0.79
SCHEMBL11692287 0.78 OPRL1 (0.32)
SCHEMBL20483727 0.78 EPHX1 (0.33) CYP2C19CYP2C9CYP1A2LMNA
SCHEMBL12986569 0.77 CYP19A1 (0.41) CYP2C19FFAR3SCN1ASCN2ASCN3A
SCHEMBL13713816 0.76 ALDH1A1 (0.35) ALOX15
SCHEMBL14519268 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673408-B1 DIMETHYL-CYCLOHEXANECARBOXYLIC ACID ESTERS IN PERFUMERY QUEST INT (NL) 1996-07-24 EP claimed