SCHEMBL8990545

SCHEMBL8990545

Nc1ccc(Nc2ccc3c(O)cc(S(=O)(=O)O)cc3c2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 4/20 0.73
NSD2 O96028 3/20 0.73
DUSP3 P51452 2/20 0.73
PTPN5 P54829 2/20 0.73
PTPN11 Q06124 2/20 0.73
CTDSP1 Q9GZU7 1/20 0.70
PRMT1 Q99873 2/20 0.63
CASP7 P55210 1/20 0.63
NT5E P21589 4/20 0.60
SNCA P37840 2/20 0.52
SIRT1 Q96EB6 1/20 0.47
RAPGEF4 Q8WZA2 1/20 0.46
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HKDC1 Q2TB90 2/20 0.44
TNNI3 P19429 1/20 0.44
TNNT2 P45379 1/20 0.44
TNNC1 P63316 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30213847 0.91 PRMT1 (0.74) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL9236771 0.91 PRMT1 (0.74) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL10524056 0.90 CASP6 (0.60) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL11721098 0.90 CASP6 (0.78) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL9722951 0.90 PRMT1 (0.68) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL29445517 0.87 CASP6 (0.82) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL1485982 0.87 CASP6 (0.82) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL9270614 0.86 SNCA (0.71) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL29240845 0.86 PRMT1 (0.63) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL11651389 0.85 CASP6 (0.59) CASP6NSD2DUSP3PTPN5PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514330-B1 Azodyes CIBA GEIGY AG (CH) 1996-07-17 EP disclosed
EP-0668327-A1 Water-soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-23 EP disclosed
US-5349057-A Water soluble azo dyes containing a cyanoamino-triazinyl-amino group and a fiber-reactive of the sulfone series HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-20 US disclosed
EP-0471713-B1 WATER-SOLUBLE AZO DYES, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST AG (DE) 1994-09-07 EP disclosed
EP-0507801-B1 AZO COMPOUNDS, PROCESS FOR PRODUCING THEM AND THEIR USE AS COLORANTS HOECHST AG (DE) 1994-08-10 EP disclosed
US-5310886-A Fiber-reactive HOECHST AKTIENGESELLSCHAFT (DE) 1994-05-10 US disclosed
US-5225545-A Colorfast CIBA-GEIGY CORPORATION (US) 1993-07-06 US disclosed
US-5204453-A Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
EP-0514330-A1 Azodyes CIBA-GEIGY AG (CH) 1992-11-19 EP disclosed
EP-0507801-A1 AZO COMPOUNDS, PROCESS FOR PRODUCING THEM AND THEIR USE AS COLORANTS. HOECHST AG (DE) 1992-10-14 EP disclosed
US-4723001-A Fibre-reactive chromium complexes and their preparation and use CIBA-GEIGY CORPORATION (US) 1988-02-02 US disclosed
US-4704133-A FIBER-REACTIVE CIBA-GEIGY CORPORATION (US) 1987-11-03 US disclosed
US-4680385-A Metal dye complexes containing an azo or azomethine dye and a colorless ligand with the C═N--N═C group CIBA-GEIGY CORPORATION (US) 1987-07-14 US disclosed
US-4678851-A FIBER-RACTIVE CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
US-4614818-A FIBER-REACTIVE DYES CIBA GEIGY CORPORATION (US) 1986-09-30 US disclosed
EP-0185611-A1 Process for the photochemical stabilisation of synthetic fibrous materials containing polyamide fibres CIBA-GEIGY AG (CH) 1986-06-25 EP disclosed
EP-0144776-A2 Fibre-reactive chromium complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-06-19 EP disclosed
EP-0142104-A2 Fibre-reactive chromium complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-05-22 EP disclosed
EP-0141416-A2 Fibre-reactive chromium complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-05-15 EP disclosed
US-4089895-A COUPLER FOR AZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1978-05-16 US disclosed