Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990580 | 1.00 | MAOB (0.48) | MAOBNFE2L2GPR183APPTRPA1 | |
| SCHEMBL7552100 | 0.88 | MAOB (0.59) | MAOBALDH1A1LMNAGAATDP1 | |
| SCHEMBL8990866 | 0.88 | RARB (0.49) | MAOBALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL8990859 | 0.88 | RARB (0.49) | MAOBALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL8990619 | 0.86 | MAOB (0.57) | MAOBALDH1A1LMNAGAATDP1 | |
| SCHEMBL8990730 | 0.86 | MAOB (0.57) | MAOBALDH1A1LMNAGAATDP1 | |
| SCHEMBL9478246 | 0.83 | SMN1; SMN2 (0.42) | GPR183ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31403433 | 0.82 | KDM4E (0.44) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL371244 | 0.82 | TAAR1 (0.56) | MAOBALDH1A1LMNAGAATDP1 | |
| SCHEMBL17068942 | 0.82 | TAAR1 (0.56) | MAOBALDH1A1LMNAGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0429558-A1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE. | MERCK PATENT GMBH (DE) | 1991-06-05 | — | — | EP | disclosed |
| WO-1990008757-A1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-09 | — | — | WO | disclosed |