Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LPL | P06858 | 1/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371244 | 1.00 | TAAR1 (0.56) | TAAR1LMNAALDH1A1GAATDP1 | |
| Ammonia Solution, Strong SCHEMBL6187599 | 0.97 | TAAR1 (0.54) | TAAR1LMNAALDH1A1GAATDP1 | |
| Hydrochloric Acid SCHEMBL7988601 | 0.97 | TAAR1 (0.54) | TAAR1LMNAALDH1A1GAATDP1 | |
| Dimethylamine SCHEMBL4661334 | 0.93 | TAAR1 (0.61) | TAAR1LMNAALDH1A1GAATDP1 | |
| SCHEMBL7552100 | 0.93 | MAOB (0.59) | TAAR1LMNAALDH1A1GAATDP1 | |
| SCHEMBL8511928 | 0.93 | TAAR1 (0.56) | TAAR1LMNAALDH1A1GAATDP1 | |
| SCHEMBL8990619 | 0.91 | MAOB (0.57) | TAAR1LMNAALDH1A1GAATDP1 | |
| SCHEMBL8990730 | 0.91 | MAOB (0.57) | TAAR1LMNAALDH1A1GAATDP1 | |
| Bicarbonate SCHEMBL3434734 | 0.89 | TDP1 (0.58) | TAAR1LMNAALDH1A1GAATDP1 | |
| SCHEMBL12013124 | 0.87 | LTA4H (0.51) | TAAR1LMNAALDH1A1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273083-B2 | Nickel fluorinating complexes and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-03-01 | — | — | US | disclosed |
| US-20150252067-A1 | NICKEL FLUORINATING COMPLEXES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252067-A1 | NICKEL FLUORINATING COMPLEXES AND USES THEREOF | SLC39A3, SLC39A14, SLC39A7 | TAAR1 3589/4885LMNA 4733/4885ALDH1A1 3058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.