Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990899 | 1.00 | DRD1 (0.47) | DRD1DAOPPARGPPARAMAOB | |
| SCHEMBL9061966 | 0.94 | DRD1 (0.52) | DRD1PPARGPPARAALDH1A1GAA | |
| SCHEMBL8990593 | 0.89 | DRD1 (0.47) | DRD1DAOPPARGPPARAMAOB | |
| SCHEMBL8990802 | 0.89 | DRD1 (0.47) | DRD1DAOPPARGPPARAMAOB | |
| SCHEMBL257110 | 0.89 | PPARG (0.50) | DRD1DAOPPARGPPARAALDH1A1 | |
| SCHEMBL8379956 | 0.87 | DRD1 (0.49) | DRD1DAOPPARGPPARAMAOB | |
| SCHEMBL8990952 | 0.86 | RARB (0.46) | DRD1DAOPPARAALDH1A1GAA | |
| SCHEMBL8990956 | 0.86 | KMT2A (0.49) | DRD1DAOMAPTRAB9APTGER4 | |
| SCHEMBL8990685 | 0.86 | RARB (0.46) | DRD1DAOPPARAALDH1A1GAA | |
| SCHEMBL9060624 | 0.86 | LMNA (0.50) | DRD1DAOPPARGPPARAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |