Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.53 |
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 6/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10381413 | 0.98 | MAOB (0.59) | MAOBFDFT1RARBTAAR1KIF11 | |
| SCHEMBL8990601 | 0.95 | MAOB (0.56) | MAOBFDFT1RARBTAAR1HDAC1 | |
| SCHEMBL17108417 | 0.93 | MAOB (0.58) | MAOBFDFT1RARBTAAR1HDAC1 | |
| SCHEMBL10382748 | 0.93 | MAOB (0.58) | MAOBFDFT1RARBTAAR1HDAC1 | |
| SCHEMBL3910376 | 0.92 | TAAR1 (0.57) | MAOBFDFT1TAAR1HDAC1HDAC8 | |
| SCHEMBL10382742 | 0.91 | MAOB (0.56) | MAOBFDFT1RARBTAAR1TSHR | |
| SCHEMBL10381412 | 0.91 | MAOB (0.56) | MAOBFDFT1RARBTAAR1TSHR | |
| SCHEMBL10381425 | 0.91 | MAOB (0.56) | MAOBFDFT1RARBTAAR1TSHR | |
| SCHEMBL10382743 | 0.91 | MAOB (0.56) | MAOBFDFT1RARBTAAR1TSHR | |
| SCHEMBL10381424 | 0.91 | MAOB (0.56) | MAOBFDFT1RARBTAAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| WO-1990008757-A1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-09 | — | — | WO | disclosed |