Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990970 | 1.00 | RARB (0.46) | RARBTSHRDAOHDAC3HDAC1 | |
| SCHEMBL9425436 | 0.98 | RARB (0.47) | RARBTSHRDAOHDAC3HDAC1 | |
| SCHEMBL9060954 | 0.98 | RARB (0.47) | RARBTSHRDAOHDAC3HDAC1 | |
| SCHEMBL8990797 | 0.95 | FAAH (0.49) | RARBTSHRDAOSLC6A4SLC6A3 | |
| SCHEMBL8990703 | 0.95 | FAAH (0.49) | RARBTSHRDAOSLC6A4SLC6A3 | |
| SCHEMBL9062396 | 0.95 | TSHR (0.49) | TSHRDAOHDAC3HDAC1HDAC2 | |
| SCHEMBL9061958 | 0.93 | FAAH (0.50) | RARBTSHRSLC6A4SLC6A3FAAH | |
| SCHEMBL9061129 | 0.93 | FAAH (0.50) | RARBTSHRSLC6A4SLC6A3FAAH | |
| SCHEMBL2056243 | 0.93 | TSHR (0.50) | TSHRDAOHDAC3HDAC1HDAC2 | |
| SCHEMBL9425365 | 0.92 | FAAH (0.53) | RARBTSHRSLC6A4SLC6A3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| WO-1990008757-A1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-09 | — | — | WO | disclosed |