Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.43 |
| ▸ | TACR1 | P25103 | 3/20 | 0.39 |
| ▸ | FPR1 | P21462 | 3/20 | 0.31 |
| ▸ | FPR2 | P25090 | 3/20 | 0.31 |
| ▸ | APOB | P04114 | 1/20 | 0.31 |
| ▸ | MTTP | P55157 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991095 | 0.92 | TACR1 (0.41) | GHSRTACR1FPR1FPR2APOB | |
| SCHEMBL8991025 | 0.92 | GHSR (0.48) | GHSRTACR1AGTR1OPRM1OPRD1 | |
| SCHEMBL8990712 | 0.90 | GHSR (0.43) | GHSRTACR1 | |
| SCHEMBL8991042 | 0.88 | GHSR (0.49) | GHSRTACR1FPR1FPR2APOB | |
| SCHEMBL8990862 | 0.87 | GHSR (0.45) | GHSRTACR1AGTR1OPRM1 | |
| SCHEMBL8991037 | 0.87 | GHSR (0.44) | GHSRTACR1AGTR1OPRM1OPRD1 | |
| SCHEMBL8991016 | 0.87 | GHSR (0.44) | GHSRTACR1AGTR1OPRM1 | |
| SCHEMBL8990774 | 0.86 | GHSR (0.49) | GHSRTACR1AGTR1OPRM1OPRD1 | |
| SCHEMBL8991059 | 0.86 | GHSR (0.50) | GHSRTACR1AGTR1OPRM1OPRD1 | |
| SCHEMBL8991017 | 0.86 | GHSR (0.49) | GHSRTACR1AGTR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |