Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664311 | 0.93 | RARB (0.48) | MAOBRARBL3MBTL1GCGRMAPK14 | |
| SCHEMBL8990931 | 0.90 | FDFT1 (0.47) | MAOBRARBL3MBTL1GCGRMAPK14 | |
| SCHEMBL9664385 | 0.90 | RARB (0.49) | RARBL3MBTL1TAAR1LMNAFDFT1 | |
| SCHEMBL9664907 | 0.88 | RARB (0.45) | RARBL3MBTL1TAAR1PTGS1PTGS2 | |
| SCHEMBL8378004 | 0.88 | RARB (0.48) | MAOBRARBTAAR1PTGS1PTGS2 | |
| SCHEMBL10975918 | 0.88 | RARB (0.50) | RARBL3MBTL1TAAR1LMNAFDFT1 | |
| SCHEMBL10981111 | 0.87 | CHKA (0.45) | RARBL3MBTL1GCGRMAPK14TAAR1 | |
| SCHEMBL9664269 | 0.87 | RARB (0.57) | RARBFDFT1CHKAHTR2A | |
| SCHEMBL8508687 | 0.87 | RARB (0.44) | MAOBRARBTAAR1CHKAGRM2 | |
| SCHEMBL16377212 | 0.86 | RARB (0.49) | MAOBRARBTAAR1CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| WO-1990008757-A1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-09 | — | — | WO | disclosed |