Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672033 | 0.95 | GRM2 (0.49) | FDFT1GRM2HTR2ARARBL3MBTL1 | |
| SCHEMBL12699499 | 0.91 | GRM2 (0.47) | FDFT1GRM2HTR2ARARBGCGR | |
| SCHEMBL8990857 | 0.90 | MAOB (0.46) | FDFT1GRM2HTR2ARARBL3MBTL1 | |
| SCHEMBL8990699 | 0.90 | RARB (0.49) | FDFT1GRM2HTR2ARARBGCGR | |
| SCHEMBL9664311 | 0.89 | RARB (0.48) | FDFT1GRM2HTR2ARARBL3MBTL1 | |
| SCHEMBL20209761 | 0.88 | RARB (0.47) | FDFT1RARBL3MBTL1GCGRMAPK14 | |
| SCHEMBL9221137 | 0.88 | RARB (0.50) | FDFT1GRM2HTR2ARARBGCGR | |
| SCHEMBL10379972 | 0.87 | RARB (0.55) | FDFT1GRM2HTR2ARARBGCGR | |
| SCHEMBL8990752 | 0.87 | RARB (0.57) | FDFT1GRM2HTR2ARARBGCGR | |
| SCHEMBL8990700 | 0.85 | RARB (0.63) | FDFT1GRM2HTR2ARARBGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |