SCHEMBL8990914

SCHEMBL8990914

O=C(NC1Cc2ccccc2CNC1=O)OCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 14/20 0.60
CTSL P07711 1/20 0.51
ASAH1 Q13510 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8990918 1.00 NAAA (0.60) NAAACTSLASAH1
SCHEMBL29481093 1.00 NAAA (0.60) NAAACTSLASAH1
SCHEMBL7423681 0.83 NAAA (0.54) NAAACTSL
SCHEMBL4818956 0.82 NAAA (0.52) NAAACTSL
SCHEMBL14193321 0.82 NAAA (0.52) NAAACTSL
SCHEMBL13818351 0.82 KAT2B (0.46) NAAA
SCHEMBL29481041 0.82 KAT2B (0.46) NAAA
SCHEMBL4079431 0.82 NAAA (0.85) NAAACTSLASAH1
SCHEMBL4073930 0.82 NAAA (0.85) NAAACTSLASAH1
SCHEMBL4073924 0.82 NAAA (0.85) NAAACTSLASAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5545735-A ANIMAL GROWTH REGULATORS MERCK & CO., INC. (US) 1996-08-13 US disclosed
WO-1995009633-A1 BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE MERCK & CO., INC. (US) 1995-04-13 WO disclosed