Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.35 |
| ▸ | DRD4 | P21917 | 5/20 | 0.35 |
| ▸ | DRD3 | P35462 | 5/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 3/20 | 0.33 |
| ▸ | FNTB | P49356 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991008 | 0.95 | GHSR (0.44) | GHSRDRD2DRD4DRD3TACR1 | |
| SCHEMBL8990862 | 0.94 | GHSR (0.45) | GHSRDRD2DRD4DRD3TACR1 | |
| SCHEMBL8991016 | 0.94 | GHSR (0.44) | GHSRDRD2DRD4DRD3TACR1 | |
| SCHEMBL8990953 | 0.93 | GHSR (0.51) | GHSRDRD2DRD4DRD3TACR1 | |
| SCHEMBL8991046 | 0.92 | GHSR (0.38) | GHSRTACR1FNTAFNTBOPRM1 | |
| SCHEMBL8990741 | 0.91 | GHSR (0.45) | GHSRDRD2DRD4DRD3TACR1 | |
| SCHEMBL8991015 | 0.91 | GHSR (0.45) | GHSRDRD2DRD4DRD3TACR1 | |
| SCHEMBL8990829 | 0.90 | GHSR (0.52) | GHSRDRD2DRD4DRD3TACR1 | |
| SCHEMBL8991037 | 0.89 | GHSR (0.44) | GHSRDRD2DRD4DRD3TACR1 | |
| SCHEMBL8990925 | 0.88 | GHSR (0.49) | GHSRTACR1OPRM1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |