Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298497 | 0.86 | HTR2A (0.41) | HTR2AHTR2CHTR2BL3MBTL1KDM4E | |
| SCHEMBL9417290 | 0.83 | ALDH1A1 (0.47) | L3MBTL1KDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL2355429 | 0.82 | ALDH1A1 (0.50) | HTR2AHTR2CHTR2BL3MBTL1KDM4E | |
| SCHEMBL29536407 | 0.82 | ALDH1A1 (0.50) | HTR2AHTR2CHTR2BL3MBTL1KDM4E | |
| SCHEMBL30715275 | 0.80 | ALDH1A1 (0.46) | HTR2AHTR2CHTR2BL3MBTL1KDM4E | |
| SCHEMBL53547 | 0.80 | ALDH1A1 (0.46) | HTR2AHTR2CHTR2BL3MBTL1KDM4E | |
| SCHEMBL30826167 | 0.80 | HTR2A (0.37) | HTR2AHTR2CHTR2BL3MBTL1KDM4E | |
| SCHEMBL8940613 | 0.80 | ALDH1A1 (0.37) | HTR2AHTR2CHTR2BL3MBTL1KDM4E | |
| SCHEMBL5226504 | 0.79 | ALDH1A1 (0.42) | L3MBTL1KDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL10042714 | 0.79 | CYP19A1 (0.40) | KDM4EALDH1A1AMY1AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5481815-A | APPARATUS FOR TREATING SEDIMENT IN A WATER BODY | HER MAJESTY THE QUEEN IN RIGHT OF CANADA, AS REPRESENTED BY THE MINISTER OF THE ENVIRONMENT (CA) | 1996-01-09 | — | — | US | disclosed |
| WO-1995001230-A1 | METHOD AND DEVICE FOR SEDIMENT DETOXIFICATION | HER MAJESTY IN RIGHT OF CANADA, represented by THE MINISTER OF THE ENVIRONMENT (CA) | 1995-01-12 | — | — | WO | disclosed |
| US-4973600-A | CONGESTIVE HEART FAILURE, GOUT, DIRUETICS, HYPERURICEMIA | TANABE SEIYAKU CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| US-4965282-A | DIURETICS | TANABE SEIYAKU CO., LTD. (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0329326-A1 | Benzodioxole derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0021294-B1 | CHEMICAL DETOXIFICATION OF TOXIC CHLORINATED AROMATIC COMPOUNDS | Vertac Chemical Corporation (US) | 1984-10-10 | — | — | EP | disclosed |
| US-4327027-A | Chemical detoxification of toxic chlorinated aromatic compounds | VERTAC CHEMICAL CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |
| EP-0021294-A1 | Chemical detoxification of toxic chlorinated aromatic compounds | Vertac Chemical Corporation (US) | 1981-01-07 | — | — | EP | disclosed |