Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 8/20 | 0.33 |
| ▸ | DRD4 | P21917 | 8/20 | 0.33 |
| ▸ | DRD3 | P35462 | 8/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | DRD5 | P21918 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | KCNK5 | O95279 | 1/20 | 0.31 |
| ▸ | KCNK17 | Q96T54 | 1/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990877 | 0.94 | GHSR (0.42) | GHSRKCNA5KCNH2DRD2DRD4 | |
| SCHEMBL8995723 | 0.93 | GHSR (0.37) | GHSRKCNA5KCNH2DRD2DRD4 | |
| SCHEMBL8990933 | 0.91 | GHSR (0.49) | GHSRDRD2DRD4DRD3 | |
| SCHEMBL8991050 | 0.91 | GHSR (0.34) | GHSRDRD2DRD4DRD3HTR1A | |
| SCHEMBL8990735 | 0.90 | GHSR (0.44) | GHSR | |
| SCHEMBL8991009 | 0.90 | GHSR (0.42) | GHSRKCNA5KCNH2DRD2DRD4 | |
| SCHEMBL8990741 | 0.88 | GHSR (0.45) | GHSRKCNA5KCNH2DRD2DRD4 | |
| SCHEMBL8990929 | 0.87 | GHSR (0.55) | GHSRKCNA5KCNH2DRD2DRD4 | |
| SCHEMBL8990855 | 0.86 | GHSR (0.48) | GHSRDRD2DRD4DRD3MEN1 | |
| SCHEMBL8990881 | 0.86 | GHSR (0.44) | GHSRKCNA5KCNH2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |