⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1220023 | 1.00 | — | — | |
| SCHEMBL8567471 | 1.00 | — | — | |
| Cyclopropane SCHEMBL7435618 | 0.96 | ITGB1 (0.36) | — | |
| SCHEMBL4777313 | 0.81 | POLB (0.34) | — | |
| SCHEMBL11445421 | 0.79 | ITGB3 (0.30) | — | |
| SCHEMBL17817929 | 0.79 | — | — | |
| SCHEMBL9646043 | 0.79 | — | — | |
| SCHEMBL29783469 | 0.77 | — | — | |
| SCHEMBL10460013 | 0.72 | ITGB3 (0.35) | — | |
| SCHEMBL630437 | 0.71 | CRBN (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3223246-A | — | — | None | — | — | JP | disclosed |
| EP-0419215-B1 | Process for preparing 4-substituted azetidinones | LILLY CO ELI (US) | 1996-07-24 | — | — | EP | disclosed |
| JP-H03223246-A | PRODUCTION OF 4-ACETOXY-2-AZETIDINONE DERIVATIVE | NIPPON SODA CO LTD | 1991-10-02 | — | — | JP | disclosed |
| EP-0419215-A2 | Process for preparing 4-substituted azetidinones | ELI LILLY AND COMPANY (US) | 1991-03-27 | — | — | EP | disclosed |
| US-4918185-A | Process for carbon-carbon bond formation at the C-4 position of 3-acylaminoazetidinones and products and starting materials therefor | ELI LILLY AND COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
| US-4771135-A | ANTIBIOTIC INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0163452-A1 | A novel process for carbon-carbon bond formation at the C-4 position of 3-acylaminoazetidinones | ELI LILLY AND COMPANY (US) | 1985-12-04 | — | — | EP | disclosed |
| US-4524028-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1985-06-18 | — | — | US | disclosed |
| US-4518533-A | Azetidinone-4-disulfides as intermediates for thia-aza compounds with a beta-lactam ring | CIBA GEIGY CORPORATION (US) | 1985-05-21 | — | — | US | disclosed |
| US-4515717-A | INTERMEDIATES FOR 6-UNSUBSTITUTED PENICILLIN ANTIOBIOTICS | CIBA GEIGY CORPORATION (US) | 1985-05-07 | — | — | US | disclosed |
| US-4500457-A | TREATING AN ACYLOXYAZETIDINONE WITH MERCAPTO COMPOUND, GLYOYLIC ESTER, HALOGENATION AGENT, AND PHOSPHINE COMPOUNT THEN CYCLIZATION | CIBA-GEIGY CORPORATION (US) | 1985-02-19 | — | — | US | disclosed |
| US-4447360-A | Intermediates for thia-aza compounds with a β-lactam ring | CIBA-GEIGY CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0008917-B1 | PENAM-3-CARBOXYLIC ACID 1,1-DIOXIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | PFIZER INC. (US) | 1982-11-24 | — | — | EP | disclosed |
| US-4331676-A | 2-PENEM COMPOUNDS UNSUBSTITUTED IN THE 6 POSITION | CIBA-GEIGY CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |
| US-4241050-A | Penam 1,1-dioxides as beta-lactamase inhibitors | PFIZER INC. (US) | 1980-12-23 | — | — | US | disclosed |
| US-4203896-A | WITH MERCURIC ACETATE AND ACETIC ACID, ACIDIC HYDROLYSIS OF N-PROPENYL GROUP | ELI LILLY AND COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| EP-0008917-A1 | Penam-3-carboxylic acid 1,1-dioxides, process for their preparation and pharmaceutical compositions | PFIZER INC. (US) | 1980-03-19 | — | — | EP | disclosed |
| US-4144232-A | Substituted azetidin-2-one antibiotics | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |