Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL149324 | 0.90 | TSHR (0.79) | TSHRCYP1A2HIF1AMAPK1TDP1 | |
| Chlorobenzene SCHEMBL2044 | 0.86 | — | — | |
| Chlorobenzene SCHEMBL1331798 | 0.86 | — | — | |
| Chlorobenzene SCHEMBL11220629 | 0.86 | TSHR (1.00) | TSHRCYP1A2LMNACYP2A6KDM4E | |
| Chlorobenzene SCHEMBL9721018 | 0.86 | TSHR (1.00) | TSHRCYP1A2LMNACYP2A6KDM4E | |
| SCHEMBL24715429 | 0.86 | TSHR (1.00) | TSHRCYP1A2LMNACYP2A6KDM4E | |
| Chlorobenzene SCHEMBL1330702 | 0.86 | — | — | |
| Chlorobenzene SCHEMBL1568605 | 0.86 | TSHR (1.00) | TSHRCYP1A2LMNACYP2A6KDM4E | |
| Chlorobenzene SCHEMBL2168046 | 0.86 | TSHR (1.00) | TSHRCYP1A2LMNACYP2A6KDM4E | |
| Chlorobenzene SCHEMBL1339852 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454004-B1 | Polyarylate and process for preparing the same | KANEGAFUCHI CHEMICAL IND (JP) | 1996-07-24 | — | — | EP | disclosed |
| US-5258483-A | Polyarylate and process for preparing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA | 1993-11-02 | — | — | US | disclosed |
| EP-0454004-A2 | Polyarylate and process for preparing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4080274-A | CATIONIC CATALYST | AMERICAN CAN COMPANY (US) | 1978-03-21 | — | — | US | disclosed |