SCHEMBL8991660

SCHEMBL8991660

O=C(OC=C1CCc2ccccc2C1=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.54
MIF P14174 9/20 0.51
MAPT P10636 5/20 0.48
PKM P14618 3/20 0.48
ALDH1A1 P00352 3/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
CES1 P23141 1/20 0.47
CYP19A1 P11511 2/20 0.46
CYP11B2 P19099 1/20 0.46
MAPK1 P28482 1/20 0.46
RAB9A P51151 3/20 0.45
NPC1 O15118 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
PLA2G1B P04054 1/20 0.45
ATG4B Q9Y4P1 1/20 0.45
POLB P06746 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9419741 0.83 MIF (0.62) MAOBMIFMAPTALDH1A1KMT2A
SCHEMBL979339 0.78 MAOB (0.58) MAOBMIFMAPTPKMALDH1A1
SCHEMBL10523264 0.77 BCHE (0.40) MAOB
SCHEMBL8548291 0.76 MAPT (0.66) MAOBMIFMAPTPKMALDH1A1
SCHEMBL8548289 0.76 MAPT (0.66) MAOBMIFMAPTPKMALDH1A1
SCHEMBL7508993 0.75 MAOB (0.58) MAOBMIFMAPTPKMALDH1A1
SCHEMBL8872375 0.75 MAOB (0.63) MAOBMIFMAPTPKMALDH1A1
SCHEMBL20359030 0.75 MAOB (0.63) MAOBMIFMAPTPKMALDH1A1
SCHEMBL30835708 0.75 MAOB (0.63) MAOBMIFMAPTPKMALDH1A1
SCHEMBL8872382 0.75 MAOB (0.63) MAOBMIFMAPTPKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0558069-B1 Process for producing 2-methyl-1-naphthol KURARAY CO (JP) 1996-07-03 EP disclosed
US-5278343-A Process for producing 2-methyl-1-naphthol KURARAY COMPANY, LTD. (JP) 1994-01-11 US disclosed
EP-0558069-A1 Process for producing 2-methyl-1-naphthol KURARAY CO., LTD. (JP) 1993-09-01 EP disclosed