Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.56 |
| ▸ | CYP27A1 | Q02318 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446419 | 0.90 | MIF (0.52) | MIFSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL8991660 | 0.83 | MAOB (0.54) | MIFSMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL7517262 | 0.79 | MIF (0.66) | MIFSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL7158711 | 0.79 | MIF (0.74) | MIFSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL2872982 | 0.79 | MIF (0.74) | MIFSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL14061927 | 0.78 | MIF (0.65) | MIFSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL4975289 | 0.78 | MIF (0.65) | MIFSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL14137061 | 0.78 | MIF (0.65) | MIFSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL8169116 | 0.77 | MIF (1.00) | MIFSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL8169114 | 0.77 | MIF (1.00) | MIFSMN1; SMN2MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101602671-B | Method for synthesizing (cis)-(6-methoxyl-1-carbonyl-3,4 dihydronaphthyl-2(1H)-ylidene) methyl benzoate | JIANGSU ZHONGDAN PHARMACEUTICAL RES COMPANY LTD | 2012-06-27 | — | — | CN | disclosed |
| CN-101602671-A | The synthetic method of (cis)-(6-methoxyl group-1-carbonyl-3,4 dihydro naphthyl-2 (1H)-subunit) methyl benzoate | JIANGSU ZHONGDAN PHARMACEUTICA (CN) | 2009-12-16 | — | — | CN | disclosed |
| US-5296508-A | Anticholesterol agents for cardiovascular disorders | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-03-22 | — | — | US | disclosed |
| US-5204373-A | Anticholesterol agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-04-20 | — | — | US | disclosed |