SCHEMBL8991803

SCHEMBL8991803

C=Cc1ccccc1C.[Na]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TSHR P16473 4/20 0.54
ACHE P22303 3/20 0.45
RAB9A P51151 3/20 0.39
KDM4E B2RXH2 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 1/20 0.39
APOBEC3A P31941 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
PABPC1 P11940 1/20 0.38
TP53 P04637 2/20 0.36
TTR P02766 1/20 0.36
CYP2D6 P10635 1/20 0.36
THPO P40225 1/20 0.36
HIF1A Q16665 1/20 0.36
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678151 0.97 ALDH1A1 (0.56) ALDH1A1TSHRACHERAB9AKDM4E
SCHEMBL29391686 0.97
SCHEMBL14887 0.97
Ammonia Solution, Strong SCHEMBL2441038 0.95 ALDH1A1 (0.54) ALDH1A1TSHRACHERAB9AKDM4E
Benzene SCHEMBL11895034 0.95 TSHR (0.54) ALDH1A1TSHRACHERAB9AKDM4E
SCHEMBL16109755 0.95 ALDH1A1 (0.54) ALDH1A1TSHRACHERAB9AKDM4E
Hydrochloric Acid SCHEMBL5155095 0.95 ALDH1A1 (0.54) ALDH1A1TSHRACHERAB9AKDM4E
SCHEMBL6843315 0.95 ALDH1A1 (0.54) ALDH1A1TSHRACHERAB9AKDM4E
Benzene SCHEMBL28875964 0.95 TSHR (0.54) ALDH1A1TSHRACHERAB9AKDM4E
SCHEMBL7547692 0.95 ALDH1A1 (0.54) ALDH1A1TSHRACHERAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5574106-A STYRENE TERPOLYMER WITH STRONG AND WEAK ACID MONOMERS ALLIED COLLOIDS LIMITED (GB) 1996-11-12 US disclosed
EP-0456390-B1 Copolymers with stain resistant properties ALLIED COLLOIDS LTD (GB) 1995-08-09 EP disclosed
EP-0452399-A4 PROPOXYLATED ALKALI-SOLUBLE THICKENERS 1992-06-03 EP disclosed
EP-0456390-A2 Copolymers with stain resistant properties Ciba Specialty Chemicals Water Treatments Limited (GB) 1991-11-13 EP disclosed
EP-0452399-A1 PROPOXYLATED ALKALI-SOLUBLE THICKENERS. UNION CARBIDE CHEM PLASTIC (US) 1991-10-23 EP disclosed
WO-1990007529-A1 PROPOXYLATED ALKALI-SOLUBLE THICKENERS DESOTO, INC. (US) 1990-07-12 WO disclosed