SCHEMBL8991892

SCHEMBL8991892

Oc1[c]cccc1-n1nc2ccccc2n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
LMNA P02545 1/20 0.45
KDM4E B2RXH2 5/20 0.41
HPGD P15428 3/20 0.41
POLB P06746 3/20 0.37
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAPT P10636 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MEN1 O00255 1/20 0.34
APAF1 O14727 1/20 0.34
TP53 P04637 1/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HTT P42858 1/20 0.33
KCNMA1 Q12791 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5847502 0.74 RAB9A (0.41) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL29363181 0.74 RAB9A (0.61) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL59309 0.74 RAB9A (0.61) NPC1RAB9ALMNAKDM4EHPGD
Methane SCHEMBL10729260 0.72 RAB9A (0.59) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL14672706 0.70 NPC1 (0.42) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL7699953 0.69 NPC1 (0.47) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL31437603 0.69 RAB9A (0.51) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL29031120 0.69 RAB9A (0.51) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL1034829 0.69 NPC1 (0.51) NPC1RAB9ALMNAKDM4EHPGD
SCHEMBL11368884 0.69 NPC1 (0.47) NPC1RAB9ALMNAKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722938-A2 Process for preparation of a radically polymerizable UV absorber based on benztriazolyl phenols RÖHM GMBH (DE) 1996-07-24 EP disclosed