Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.58 |
| ▸ | DRD3 | P35462 | 8/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332925 | 1.00 | DRD2 (0.58) | DRD2DRD3DRD4HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL7355128 | 0.99 | DRD2 (0.57) | DRD2DRD3DRD4HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL7331556 | 0.99 | DRD2 (0.57) | DRD2DRD3DRD4HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL7336177 | 0.99 | DRD2 (0.57) | DRD2DRD3DRD4HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL7801369 | 0.99 | DRD2 (0.57) | DRD2DRD3DRD4HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL7329632 | 0.87 | DRD2 (0.55) | DRD2DRD3DRD4HTR1A | |
| Hydrochloric Acid SCHEMBL7330498 | 0.85 | DRD3 (0.53) | DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7330503 | 0.85 | DRD3 (0.53) | DRD2DRD3DRD4 | |
| SCHEMBL8044364 | 0.85 | DRD2 (0.82) | DRD2DRD3DRD4HTR1A | |
| Hydrochloric Acid SCHEMBL7338118 | 0.84 | DRD3 (0.53) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719252-A1 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1996-07-03 | — | — | EP | disclosed |