Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.77 |
| ▸ | PPARG | P37231 | 16/20 | 0.55 |
| ▸ | PPARA | Q07869 | 16/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799156 | 0.87 | KDR (0.76) | KDRPPARGPPARAFFAR1CYP2C9 | |
| SCHEMBL4034790 | 0.87 | KDR (1.00) | KDRPPARGPPARAFFAR1CYP2C9 | |
| SCHEMBL6965127 | 0.85 | KDR (0.69) | KDRPPARGPPARAFFAR1CYP2C9 | |
| SCHEMBL6965135 | 0.85 | KDR (0.69) | KDRPPARGPPARAFFAR1CYP2C9 | |
| SCHEMBL6160505 | 0.84 | KDR (0.77) | KDRPPARGPPARAFFAR1CYP2C9 | |
| SCHEMBL12617678 | 0.83 | KDR (0.80) | KDRPPARGPPARAFFAR1CYP2C9 | |
| SCHEMBL4033640 | 0.82 | KDR (0.79) | KDRPPARGPPARAFFAR1CYP2C9 | |
| SCHEMBL8340250 | 0.82 | KDR (0.78) | KDRPPARGPPARAFFAR1CYP2C9 | |
| SCHEMBL8983760 | 0.82 | KDR (0.78) | KDRPPARGPPARAFFAR1CYP2C9 | |
| SCHEMBL14514345 | 0.82 | KDR (0.78) | KDRPPARGPPARAFFAR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510360-A | ADMINISTERING ORALLY, SIDE EFFECT REDUCTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-04-23 | — | — | US | disclosed |