Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7292653 | 0.94 | SNCA (0.64) | SNCALMNAKAT6AALDH1A1AKR1C3 | |
| SCHEMBL28275730 | 0.92 | SNCA (0.65) | SNCALMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL1556 | 0.92 | SNCA (0.65) | SNCALMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL29857297 | 0.92 | SNCA (0.65) | SNCALMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL304050 | 0.92 | SNCA (0.65) | SNCALMNAALDH1A1TSHRL3MBTL1 | |
| Naphthalene SCHEMBL28216326 | 0.92 | SNCA (0.65) | SNCALMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL29357423 | 0.92 | SNCA (0.65) | SNCALMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL8923372 | 0.90 | TSHR (0.64) | SNCALMNAKAT6AALDH1A1AKR1C3 | |
| SCHEMBL9888352 | 0.90 | SNCA (0.62) | SNCALMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL1457860 | 0.90 | SNCA (0.62) | SNCALMNAALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170266151-A1 | Novel salts of 3-[(DIMETHYLAMINO)METHYL]-N--1-BENZOFURAN-2-CARBOXAMIDE, related crystalline forms, method for preparing the same and pharmaceutical compositions containing the same | PHARMACYCLICS LLC (US) | 2017-09-21 | — | — | US | disclosed |
| US-5510378-A | Retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1996-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170266151-A1 | Novel salts of 3-[(DIMETHYLAMINO)METHYL]-N--1-BENZOFURAN-2-CARBOXAMIDE, related crystalline forms, method for preparing the same and pharmaceutical compositions containing the same | CA1, CA13, CA12 | SNCA 547/4885LMNA 3922/4885KAT6A 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.