⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144605 | 0.88 | — | — | |
| SCHEMBL9723623 | 0.88 | — | — | |
| SCHEMBL24499436 | 0.75 | — | — | |
| SCHEMBL5147023 | 0.73 | — | — | |
| SCHEMBL24499433 | 0.73 | — | — | |
| SCHEMBL9561617 | 0.71 | — | — | |
| SCHEMBL15434495 | 0.71 | TET2 (0.30) | — | |
| SCHEMBL5165154 | 0.71 | DGAT1 (0.30) | — | |
| SCHEMBL9225511 | 0.70 | — | — | |
| SCHEMBL16409373 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340558-B1 | Light guide | HOECHST AG (DE) | 1996-07-31 | — | — | EP | disclosed |
| US-5319131-A | Reacting dimethyl 2-fluoromalonate with formaldehyde to form hydroxymethylated dimethyl 2-flurormalonate, hydrolysis, decarboxylation, dehydration then esterification with a hexafluoroalkylol | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-07 | — | — | US | disclosed |
| US-5239027-A | Optical fibers | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-24 | — | — | US | disclosed |
| US-5198925-A | α-fluoroacrylic acid esters and polymers thereof | HOECHST AKTIENGESELLSCHAFT | 1993-03-30 | — | — | US | disclosed |
| US-5187769-A | Comonomers of fluorinated acrylates, deuterium-substituted fluoroacrylates forming core/cladding structure of optical fibers; high glass transition temperature | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| EP-0501424-A1 | Transparent thermoplastic moulding composition, process for its preparation and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-02 | — | — | EP | disclosed |
| US-4991932-A | Optical waveguide | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| EP-0203462-B1 | ALPHA-FLUOROACRYLIC-ACID ESTERS AND THEIR POLYMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-01 | — | — | EP | disclosed |
| EP-0340558-A2 | Light guide | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-11-08 | — | — | EP | disclosed |
| EP-0203462-A2 | Alpha-fluoroacrylic-acid esters and their polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-12-03 | — | — | EP | disclosed |