Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | CTSG | P08311 | 3/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.44 |
| ▸ | CMA1 | P23946 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27741659 | 0.82 | MMP2 (0.47) | SLC6A2SLC6A3PRSS1CTSGCTRB1 | |
| SCHEMBL27952015 | 0.81 | MAPT (0.55) | SLC6A2SLC6A3PRSS1CTSGCTRB1 | |
| SCHEMBL8388151 | 0.81 | MMP2 (0.46) | SLC6A2SLC6A3PRSS1CTSGCTRB1 | |
| SCHEMBL11053944 | 0.80 | SLC6A2 (0.48) | SLC6A2SLC6A3PRSS1CTSGCTRB1 | |
| SCHEMBL27261414 | 0.78 | CNR2 (0.45) | PRSS1CNR2MAPTALDH1A1ATM | |
| SCHEMBL6582699 | 0.78 | SLC6A2 (0.47) | SLC6A2SLC6A3PRSS1CTSGCTRB1 | |
| SCHEMBL28770741 | 0.78 | MMP2 (0.58) | SLC6A2SLC6A3PRSS1CTSGCTRB1 | |
| SCHEMBL7066806 | 0.77 | MDM2 (0.52) | SLC6A2SLC6A3PRSS1CTSGCTRB1 | |
| SCHEMBL9576675 | 0.77 | MMP2 (0.61) | SLC6A2SLC6A3PRSS1CTSGCTRB1 | |
| SCHEMBL6582853 | 0.77 | MMP2 (0.48) | SLC6A2SLC6A3PRSS1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433826-B1 | Fluorophenylpyridines | HOECHST AG (DE) | 1996-07-10 | — | — | EP | disclosed |
| US-5204476-A | For use in chiral tilted smectic liquid crystal phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-20 | — | — | US | disclosed |
| EP-0433826-A2 | Fluorophenylpyridines | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-26 | — | — | EP | disclosed |