Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
| ▸ | RELA | Q04206 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | TACR2 | P21452 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449622 | 1.00 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9325708 | 0.87 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9325596 | 0.87 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9327014 | 0.87 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9326707 | 0.86 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9326991 | 0.86 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9328544 | 0.85 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9328291 | 0.85 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9327237 | 0.85 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9154201 | 0.85 | RARB (0.51) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433826-B1 | Fluorophenylpyridines | HOECHST AG (DE) | 1996-07-10 | — | — | EP | disclosed |
| US-5204476-A | For use in chiral tilted smectic liquid crystal phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-20 | — | — | US | disclosed |
| EP-0433826-A2 | Fluorophenylpyridines | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-26 | — | — | EP | disclosed |