Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 10/20 | 0.61 |
| ▸ | MAOA | P21397 | 8/20 | 0.61 |
| ▸ | MAOB | P27338 | 8/20 | 0.61 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481698 | 0.95 | KDM1A (0.59) | KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL28347051 | 0.84 | KDM1A (0.47) | KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL28420235 | 0.77 | KDM1A (0.56) | KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL15767411 | 0.76 | KDM1A (1.00) | KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL11788215 | 0.76 | KDM1A (1.00) | KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL15767592 | 0.76 | KDM1A (1.00) | KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL15777295 | 0.76 | KDM1A (1.00) | KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL15777297 | 0.76 | KDM1A (1.00) | KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL11374745 | 0.76 | KDM1A (0.44) | KDM1AMAOAMAOB | |
| SCHEMBL11374721 | 0.76 | KDM1A (0.44) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445749-B1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-4141993-A | ANTIDEPRESSANTS | ASTRA LAKEMEDEL AKTIEBOLAGET (SE) | 1979-02-27 | — | — | US | disclosed |
| US-4141993-A | ANTIDEPRESSANTS | ASTRA LAKEMEDEL AKTIEBOLAGET (SE) | 1979-02-27 | — | — | US | disclosed |
| US-4053637-A | ANTIDEPRESSANTS | ASTRA LAKEMEDAL AKTIEBOLAG (SW) | 1977-10-11 | — | — | US | disclosed |