SCHEMBL2481698

SCHEMBL2481698

NC1(c2ccccc2)CCCCC1c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 9/20 0.59
MAOA P21397 7/20 0.59
MAOB P27338 7/20 0.59
RCOR1 Q9UKL0 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8992430 0.95 KDM1A (0.61) KDM1AMAOAMAOBRCOR1
SCHEMBL28347051 0.89 KDM1A (0.47) KDM1AMAOAMAOBRCOR1
SCHEMBL8777356 0.78 OPRL1 (0.44) KDM1AMAOAMAOB
SCHEMBL9295240 0.78 KDM1A (0.44) KDM1AMAOAMAOB
SCHEMBL23595697 0.76
SCHEMBL14652769 0.76 KDM1A (0.60) KDM1AMAOAMAOB
SCHEMBL31143852 0.76 KDM1A (0.43) KDM1AMAOAMAOB
SCHEMBL23595698 0.76
SCHEMBL6356774 0.76 KDM1A (0.43) KDM1AMAOAMAOB
SCHEMBL6356771 0.76 KDM1A (0.43) KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115286657-A Continuous production method of hydroxymethyl phosphonate 湖北理工学院 2022-11-04 CN claimed
US-9187504-B2 Method of making hydroxymethylphosphonate ICL-IP AMERICA INC. (US) 2015-11-17 US claimed
EP-2376507-B1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATES ICL IP AMERICA INC (US) 2013-05-15 EP claimed
US-8198341-B2 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom ICL-IP AMERICA INC. (US) 2012-06-12 US claimed
US-20110257287-A1 Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom STOWELL JEFFREY K 2011-10-20 US claimed
EP-2376507-A1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM ICL-IP America Inc. (US) 2011-10-19 EP claimed
WO-2010080425-A1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM SUPRESTA LLC. (US) 2010-07-15 WO claimed
US-20100160468-A1 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom ICL-IP AMERICA INC. 2010-06-24 US claimed
CN-115286657-A Continuous production method of hydroxymethyl phosphonate 湖北理工学院 2022-11-04 CN disclosed
CN-107383093-B Hydroxymethylphosphonate, compositions, polyurethane foams, and articles ICL-IP美国有限公司 2021-07-16 CN disclosed
EP-3553068-B1 YDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM ICL IP AMERICA INC (US) 2021-04-28 EP disclosed
EP-3553068-A1 HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM ICL-IP America Inc. (US) 2019-10-16 EP disclosed
EP-2589701-B1 METHOD FOR PRODUCING SIZING AGENT-COATED CARBON FIBERS, AND SIZING AGENT-COATED CARBON FIBERS TORAY INDUSTRIES (JP) 2019-08-21 EP disclosed
EP-2909218-B1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM ICL IP AMERICA INC (US) 2019-07-10 EP disclosed
US-4461818-A ETHCING WITH SOLUTION OF ALKALI AND/OR ALCOHOL MITSUBISHI PAPER MILLS LTD. (JP) 1984-07-24 US disclosed
US-4461821-A Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound FUJI PHOTO FILM CO., LTD. (JP) 1984-07-24 US disclosed
US-4448869-A HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE FUJI PHOTO FILM CO., LTD. (JP) 1984-05-15 US disclosed
US-4447515-A DIACYLAMINE COMPOUND ADDED FUJI PHOTO FILM CO., LTD. (JP) 1984-05-08 US disclosed
US-4444863-A UREA COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1984-04-24 US disclosed
US-4387149-A CATIONIC DYES; STABILITY; COPYING MITSUBISHI PAPER MILLS, LTD. (JP) 1983-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110257287-A1 Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom PFAS, PGM2, NEFM KDM1A 1152/4885MAOA 1337/4885MAOB 1570/4885
US-20100160468-A1 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom PFAS, PGM2, NEFM KDM1A 1152/4885MAOA 1337/4885MAOB 1570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.