Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992436 | 0.82 | NPSR1 (0.43) | NPSR1NQO2ALDH1A1GFERHTT | |
| SCHEMBL4908857 | 0.82 | L3MBTL1 (0.41) | NPSR1GFERBCHETDP1MEN1 | |
| SCHEMBL5267308 | 0.81 | NPSR1 (0.45) | NPSR1NQO2ALDH1A1GFERHTT | |
| SCHEMBL5263014 | 0.77 | NPSR1 (0.42) | NPSR1NQO2ALDH1A1GFERHTT | |
| SCHEMBL14736334 | 0.76 | IDO1 (0.51) | NPSR1NQO2ALDH1A1GFERHTT | |
| SCHEMBL5691656 | 0.75 | NPSR1 (0.45) | NPSR1NQO2ALDH1A1GFERHTT | |
| SCHEMBL14736426 | 0.75 | IDO1 (0.58) | NQO2IDO1BCHE | |
| SCHEMBL1928104 | 0.74 | IDO1 (0.49) | NQO2IDO1BCHE | |
| SCHEMBL14736076 | 0.74 | IDO1 (0.55) | NQO2ALDH1A1IDO1BCHEDRD2 | |
| SCHEMBL1196852 | 0.74 | CYP17A1 (0.42) | NPSR1NQO2HTTIDO1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510354-A | HYPOTENSIVE AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |