Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | STK17B | O94768 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178069 | 0.82 | ALDH1A1 (0.54) | ALDH1A1GFERHTTNPSR1MEN1 | |
| SCHEMBL10178199 | 0.81 | HSP90AA1 (0.51) | ALDH1A1GFERMEN1KMT2ANAMPT | |
| SCHEMBL23035056 | 0.80 | ALDH1A1 (0.49) | ALDH1A1GFERHTTNPSR1MEN1 | |
| SCHEMBL20451407 | 0.80 | ALDH1A1 (0.49) | ALDH1A1GFERHTTNPSR1GAA | |
| SCHEMBL1843221 | 0.79 | ALDH1A1 (0.48) | ALDH1A1GFERHTTNPSR1MEN1 | |
| SCHEMBL5531682 | 0.78 | TDP1 (0.48) | ALDH1A1GFERHTTMEN1GAA | |
| SCHEMBL28230449 | 0.77 | ALDH1A1 (0.43) | ALDH1A1GFERDRD2CA1CA2 | |
| SCHEMBL29651714 | 0.75 | STK17B (0.41) | ALDH1A1GFERMEN1GAAKMT2A | |
| SCHEMBL14420521 | 0.75 | TDP1 (0.47) | ALDH1A1GFERMEN1GAAKMT2A | |
| SCHEMBL9043069 | 0.75 | ALDH1A1 (0.42) | ALDH1A1GFERHTTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510354-A | HYPOTENSIVE AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |