Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PON1 | P27169 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2149004 | 0.93 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL897977 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| Acetonitrile SCHEMBL18093207 | 0.89 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| Acetonitrile SCHEMBL14637715 | 0.89 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL180235 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL8169330 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL6750309 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL9931725 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL14859660 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL60789 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921589-B2 | Electrolyte formulations | MERCK PATENT GMBH (DE) | 2014-12-30 | — | — | US | disclosed |
| US-8829201-B2 | Electrolyte Formulations | MERCK PATENT GMBH (DE) | 2014-09-09 | — | — | US | disclosed |
| EP-2622617-A2 | ELECTROLYTE FORMULATIONS | Merck Patent GmbH (DE) | 2013-08-07 | — | — | EP | disclosed |
| US-20130180591-A1 | ELECTROLYTE FORMULATIONS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-07-18 | — | — | US | disclosed |
| US-20120318360-A1 | Electrolyte Formulations | MERCK PATENT GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| WO-2012041437-A2 | ELECTROLYTE FORMULATIONS | MERCK PATENT GMBH (DE) | 2012-04-05 | — | — | WO | disclosed |
| WO-2011085964-A1 | ELECTROLYTE FORMULATIONS | MERCK PATENT GMBH (DE) | 2011-07-21 | — | — | WO | disclosed |
| JP-2004175666-A | ONIUM SALT | TOKUYAMA CORP | 2004-06-24 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120318360-A1 | Electrolyte Formulations | NHERF1, HCN4, DDT | SMN1; SMN2 4519/4885MEN1 1923/4885APAF1 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.