⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430757 | 0.83 | — | — | |
| SCHEMBL2244036 | 0.80 | — | — | |
| SCHEMBL2243490 | 0.77 | — | — | |
| SCHEMBL2503508 | 0.75 | — | — | |
| SCHEMBL8847313 | 0.75 | CA12 (0.35) | — | |
| SCHEMBL1470033 | 0.73 | — | — | |
| SCHEMBL17784247 | 0.73 | CYP2C19 (0.36) | — | |
| SCHEMBL13453129 | 0.71 | — | — | |
| SCHEMBL10951253 | 0.69 | CA12 (0.41) | — | |
| SCHEMBL10954180 | 0.69 | CA12 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531948-B1 | Process for preparation of bis- and tris(silylorgano)-amines | DOW CORNING (US) | 1996-07-10 | — | — | EP | disclosed |
| EP-0531948-A1 | Process for preparation of bis- and tris(silylorgano)-amines | DOW CORNING CORPORATION (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5101055-A | From the corresponding mono- and di-compounds, palladium monoxide catalyst | DOW CORNING CORPORATION (US) | 1992-03-31 | — | — | US | disclosed |