⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430757 | 0.87 | — | — | |
| SCHEMBL646688 | 0.82 | NFKB1 (0.35) | — | |
| SCHEMBL2243490 | 0.80 | — | — | |
| SCHEMBL9331980 | 0.80 | — | — | |
| SCHEMBL8992656 | 0.80 | — | — | |
| SCHEMBL2503508 | 0.78 | — | — | |
| SCHEMBL1023534 | 0.77 | NFKB1 (0.32) | — | |
| SCHEMBL6277270 | 0.77 | NFKB1 (0.39) | — | |
| SCHEMBL1470033 | 0.76 | — | — | |
| SCHEMBL16363207 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367855-B2 | Process for preparing silylorganoamines | EVONIK DEGUSSA GMBH (DE) | 2013-02-05 | — | — | US | disclosed |
| EP-2361916-B1 | Method for manufacturing silylorganoamines | EVONIK DEGUSSA GMBH (DE) | 2012-10-31 | — | — | EP | disclosed |
| EP-2361916-A1 | Method for manufacturing silylorganoamines | Evonik Degussa GmbH (DE) | 2011-08-31 | — | — | EP | disclosed |
| EP-2361917-A1 | Method for manufacturing silylorganoamines | Evonik Degussa GmbH (DE) | 2011-08-31 | — | — | EP | disclosed |
| US-20110201835-A1 | Process for Preparing Silylorganoamines | EVONIK DEGUSSA GMBH (DE) | 2011-08-18 | — | — | US | disclosed |
| EP-0531948-B1 | Process for preparation of bis- and tris(silylorgano)-amines | DOW CORNING (US) | 1996-07-10 | — | — | EP | disclosed |
| US-5393353-A | Immersion of alloy surface in phosphorous acid selected from phosphoric, phosphorous or hypophosphoric acid and mixture containing atleast one silane compound; removal, drying | MCGEAN-ROHCO, INC. (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0531948-A1 | Process for preparation of bis- and tris(silylorgano)-amines | DOW CORNING CORPORATION (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5101055-A | From the corresponding mono- and di-compounds, palladium monoxide catalyst | DOW CORNING CORPORATION (US) | 1992-03-31 | — | — | US | disclosed |