SCHEMBL8992710

SCHEMBL8992710

CCC(NC(CC)[Si](OC)(OC)c1ccccc1)[Si](OC)(OC)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6144719 0.79 LMNA (0.34) LMNAHTT
SCHEMBL4999817 0.77 LMNA (0.33) LMNA
SCHEMBL2244551 0.76 SLC6A2 (0.32) LMNA
SCHEMBL22551437 0.76 LMNA (0.32) LMNA
SCHEMBL30502380 0.76 LMNA (0.32) LMNA
SCHEMBL30502381 0.76 LMNA (0.32) LMNA
SCHEMBL2242675 0.76 LMNA (0.32) LMNA
SCHEMBL21630244 0.74 GRIN1 (0.32) LMNAHTT
SCHEMBL5423659 0.73 CA4 (0.36) LMNA
SCHEMBL540729 0.73 LMNA (0.31) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531948-B1 Process for preparation of bis- and tris(silylorgano)-amines DOW CORNING (US) 1996-07-10 EP disclosed
EP-0531948-A1 Process for preparation of bis- and tris(silylorgano)-amines DOW CORNING CORPORATION (US) 1993-03-17 EP disclosed
US-5101055-A From the corresponding mono- and di-compounds, palladium monoxide catalyst DOW CORNING CORPORATION (US) 1992-03-31 US disclosed