Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 3/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009472 | 1.00 | PPM1D (0.36) | PPM1DCDC25ACDC25B | |
| SCHEMBL3302592 | 0.91 | PPM1D (0.35) | PPM1DCDC25ACDC25B | |
| SCHEMBL13588131 | 0.91 | PPM1D (0.35) | PPM1DCDC25ACDC25B | |
| SCHEMBL7105132 | 0.91 | PPM1D (0.35) | PPM1DCDC25ACDC25B | |
| SCHEMBL13392744 | 0.91 | PPM1D (0.35) | PPM1DCDC25ACDC25B | |
| SCHEMBL14005447 | 0.88 | PPM1D (0.35) | PPM1DCDC25ACDC25B | |
| SCHEMBL13588136 | 0.86 | PPM1D (0.32) | PPM1D | |
| SCHEMBL3259396 | 0.86 | PPM1D (0.32) | PPM1D | |
| SCHEMBL13392742 | 0.86 | PPM1D (0.32) | PPM1D | |
| SCHEMBL3302550 | 0.86 | PPM1D (0.32) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585368-A | SKIN DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| EP-0647219-B1 | DERIVATIVES IN THE VITAMIN D SERIES MODIFIED AT THE 20 POSITION, A METHOD OF PREPARING SUCH DERIVATIVES, INTERMEDIATES USED IN THIS METHOD, PHARMACEUTICAL PREPARATIONS CONTAINING THE DERIVATIVES AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AG (DE) | 1996-07-31 | — | — | EP | disclosed |