Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 2/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105132 | 0.91 | PPM1D (0.35) | PPM1DCDC25ACDC25B | |
| SCHEMBL13588131 | 0.91 | PPM1D (0.35) | PPM1DCDC25ACDC25B | |
| SCHEMBL13392744 | 0.91 | PPM1D (0.35) | PPM1DCDC25ACDC25B | |
| SCHEMBL3302592 | 0.91 | PPM1D (0.35) | PPM1DCDC25ACDC25B | |
| SCHEMBL3302550 | 0.89 | PPM1D (0.32) | PPM1D | |
| SCHEMBL3259396 | 0.89 | PPM1D (0.32) | PPM1D | |
| SCHEMBL13588136 | 0.89 | PPM1D (0.32) | PPM1D | |
| SCHEMBL13392742 | 0.89 | PPM1D (0.32) | PPM1D | |
| SCHEMBL8992725 | 0.88 | PPM1D (0.36) | PPM1DCDC25ACDC25B | |
| SCHEMBL9009472 | 0.88 | PPM1D (0.36) | PPM1DCDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280859-A1 | GEMINI VITAMIN D3 COMPOUNDS AND METHODS OF USE THEREOF | BIOXELL S.P.A. (IT) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280859-A1 | GEMINI VITAMIN D3 COMPOUNDS AND METHODS OF USE THEREOF | VDR, GC, CYP24A1 | PPM1D 3901/4885CDC25A 2295/4885CDC25B 2421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.