Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | GBA1 | P04062 | 5/20 | 0.43 |
| ▸ | FGF1 | P05230 | 3/20 | 0.33 |
| ▸ | FGF2 | P09038 | 3/20 | 0.33 |
| ▸ | VEGFA | P15692 | 3/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992782 | 1.00 | TNF (0.46) | TNFGBA1FGF1FGF2VEGFA | |
| SCHEMBL12670465 | 0.93 | TNF (0.40) | TNFGBA1SSTR1SSTR2SSTR4 | |
| SCHEMBL26824612 | 0.93 | TNF (0.40) | TNFGBA1SSTR1SSTR2SSTR4 | |
| SCHEMBL17189161 | 0.93 | TNF (0.40) | TNFGBA1SSTR1SSTR2SSTR4 | |
| SCHEMBL15304397 | 0.93 | TNF (0.40) | TNFGBA1SSTR1SSTR2SSTR4 | |
| SCHEMBL17371173 | 0.93 | TNF (0.40) | TNFGBA1SSTR1SSTR2SSTR4 | |
| SCHEMBL15981300 | 0.93 | TNF (0.40) | TNFGBA1SSTR1SSTR2SSTR4 | |
| SCHEMBL6574204 | 0.89 | GBA1 (0.46) | TNFGBA1FGF1FGF2VEGFA | |
| SCHEMBL8992926 | 0.89 | GBA1 (0.46) | TNFGBA1FGF1FGF2VEGFA | |
| SCHEMBL6574209 | 0.89 | GBA1 (0.46) | TNFGBA1FGF1FGF2VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021231-B1 | PROCESS FOR THE PREPARATION OF 5'-DEOXY-5-FLUORO URIDINE AND INTERMEDIATES IN THIS PROCESS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-10-05 | — | — | EP | claimed |
| EP-0602478-B1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 1996-07-31 | — | — | EP | disclosed |
| EP-0021231-B1 | PROCESS FOR THE PREPARATION OF 5'-DEOXY-5-FLUORO URIDINE AND INTERMEDIATES IN THIS PROCESS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-10-05 | — | — | EP | disclosed |
| US-4340729-A | 5'-Deoxy-5-fluorouridine | HOFFMANN-LA ROCHE INC. (US) | 1982-07-20 | — | — | US | disclosed |