Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15981300 | 1.00 | TNF (0.40) | TNFGBA1SSTR1SSTR2SSTR4 | |
| SCHEMBL26824612 | 1.00 | TNF (0.40) | TNFGBA1SSTR1SSTR2SSTR4 | |
| SCHEMBL12670465 | 1.00 | TNF (0.40) | TNFGBA1SSTR1SSTR2SSTR4 | |
| SCHEMBL17371173 | 1.00 | TNF (0.40) | TNFGBA1SSTR1SSTR2SSTR4 | |
| SCHEMBL15304397 | 1.00 | TNF (0.40) | TNFGBA1SSTR1SSTR2SSTR4 | |
| SCHEMBL8992782 | 0.93 | TNF (0.46) | TNFGBA1SSTR1SSTR2SSTR4 | |
| SCHEMBL8992784 | 0.93 | TNF (0.46) | TNFGBA1SSTR1SSTR2SSTR4 | |
| SCHEMBL16135483 | 0.85 | TNF (0.33) | TNF | |
| SCHEMBL14714134 | 0.85 | GBA1 (0.47) | TNFGBA1 | |
| SCHEMBL15045698 | 0.85 | TNF (0.43) | TNFGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246324-A2 | PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USES THEREOF | Tianjin Institute Of Pharmaceutical Research (CN) | 2017-11-22 | — | — | EP | disclosed |
| EP-2933250-B1 | PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USE THEREOF | TIANJIN INST OF PHARMACEUTICAL RES (CN) | 2017-08-09 | — | — | EP | disclosed |
| US-20170057989-A1 | PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USE THEREOF | TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH (CN) | 2017-03-02 | — | — | US | disclosed |
| US-9505734-B2 | Phenyl C-glucoside derivative containing deoxyglucose structure, preparation method and use thereof | TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH (CN) | 2016-11-29 | — | — | US | disclosed |
| EP-2933250-A1 | PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USE THEREOF | Tianjin Institute Of Pharmaceutical Research (CN) | 2015-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170057989-A1 | PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USE THEREOF | GCG, SLC5A1, DPP7 | TNF 1688/4885GBA1 692/4885SSTR1 1815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.