Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.73 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387801 | 0.86 | ITGB3 (0.73) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL8992972 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2BKDM4EALDH1A1HPGD | |
| SCHEMBL8993122 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL8992929 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL8798199 | 0.83 | ITGB3 (0.69) | ITGB3ITGA2B | |
| SCHEMBL7359659 | 0.82 | ITGB3 (0.74) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL8993356 | 0.81 | ITGB3 (0.50) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL8993076 | 0.81 | ITGB3 (0.51) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL8993058 | 0.81 | ITGB3 (0.53) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL8993287 | 0.79 | ITGB3 (0.49) | ITGB3ITGA2BKDM4EALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5493020-A | ANTICOAGULANTS | GENENTECH, INC. (US) | 1996-02-20 | — | — | US | disclosed |