Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472225 | 0.91 | HPGD (0.50) | MAPTALDH1A1SMN1; SMN2ESR1ESR2 | |
| SCHEMBL5955919 | 0.85 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2ESR1ESR2CYP3A4 | |
| SCHEMBL2689876 | 0.83 | ESR1 (0.67) | MAPTALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL11586013 | 0.83 | ALDH1A1 (0.61) | MAPTALDH1A1SMN1; SMN2ESR1ESR2 | |
| Bicarbonate SCHEMBL10822897 | 0.82 | ESR1 (0.65) | MAPTALDH1A1ESR1ESR2CYP3A4 | |
| Bicarbonate SCHEMBL5607713 | 0.82 | ESR1 (0.65) | MAPTALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL20346185 | 0.82 | MAPT (0.69) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2610305 | 0.82 | MAPT (0.55) | MAPTALDH1A1SMN1; SMN2KIF11HPGD | |
| SCHEMBL7929159 | 0.82 | MAOB (0.49) | MAPTALDH1A1SMN1; SMN2ESR1ESR2 | |
| SCHEMBL11623379 | 0.82 | MAPT (0.55) | MAPTALDH1A1SMN1; SMN2KIF11HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671169-B2 | Polycarbonate-polyester block copolymer compositions, methods, and articles | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-03-02 | — | — | US | disclosed |
| US-20080300379-A1 | POLYCARBONATE-POLYESTER BLOCK COPOLYMER COMPOSITIONS, METHODS, AND ARTICLES | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2008-12-04 | — | — | US | disclosed |
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| US-4202894-A | AGRICULTURE | HOFFMANN-LA ROCHE INC. (US) | 1980-05-13 | — | — | US | disclosed |